What is the coefficient of $x^{20}y^{35}$ in the expansion of $(5x - 3y)^{55}$?
$(5x - 3y)^{55}$
$= \sum_{k=0}^{55} \binom{55}{k} (5x)^{k} (-3y)^{55-k}$
$= \binom{55}{20} (5x)^{20} (-3y)^{35}$
$= \binom{55}{20} 5^{20} x^{20} (-3)^{35} y^{35}$
$= - \binom{55}{20} 5^{20} 3^{35} x^{20} y^{35}$
Thus, the coefficient of $x^{20}y^{35}$ is $- \binom{55}{20} 5^{20} 3^{35}$.